Selpercatinib
Basic Information
| Item | Value |
|---|---|
| DrugBank ID | DB15685 |
| Evidence Level | L5 (Computational Prediction) |
| Number of Predicted Indications | 59 |
Predicted Indications (TxGNN)
The following are potential new indications predicted by the TxGNN model. Higher scores indicate higher predicted relevance.
| # | Indication | Source |
|---|---|---|
| 1 | pulmonary hypertension | KG + DL |
| 2 | migraine disorder | KG + DL |
| 3 | migraine with brainstem aura | KG + DL |
| 4 | kyphoscoliotic heart disease | KG + DL |
| 5 | migraine with or without aura, susceptibility to | KG + DL |
| 6 | pulmonary hypertension, primary, autosomal recessive | KG + DL |
| 7 | obsolete patella aplasia, coxa vara, and tarsal synostosis | KG + DL |
| 8 | idiopathic pulmonary arterial hypertension | KG + DL |
| 9 | atrophoderma vermiculata | KG + DL |
| 10 | coxopodopatellar syndrome | KG + DL |
| 11 | familial clubfoot due to 17q23.1q23.2 microduplication | KG + DL |
| 12 | chromosome 17q23.1-q23.2 deletion syndrome | KG + DL |
| 13 | pulmonary hypertension, primary | KG + DL |
| 14 | ulerythema ophryogenesis | KG + DL |
| 15 | idiopathic and/or familial pulmonary arterial hypertension | KG + DL |
| 16 | hypertrichosis (disease) | KG + DL |
| 17 | gastrointestinal hamartoma | KG + DL |
| 18 | pulmonary arterial hypertension | KG + DL |
| 19 | malformation syndrome with odontal and/or periodontal component | KG + DL |
| 20 | Ambras type hypertrichosis universalis congenita | KG + DL |
| 21 | cor pulmonale | KG + DL |
| 22 | syndrome with a Dandy-Walker malformation as major feature | KG + DL |
| 23 | isolated genetic hair shaft abnormality | KG + DL |
| 24 | heritable pulmonary arterial hypertension | KG + DL |
| 25 | amenorrhea (disease) | KG + DL |
| 26 | primary hereditary glaucoma | KG + DL |
| 27 | headache disorder | KG + DL |
| 28 | open-angle glaucoma | KG + DL |
| 29 | Prinzmetal angina | KG + DL |
| 30 | peripheral vascular disease | KG + DL |
| 31 | Raynaud disease | KG + DL |
| 32 | trigeminal autonomic cephalalgia | KG + DL |
| 33 | pulmonary arterial hypertension associated with congenital heart disease | KG + DL |
| 34 | pulmonary arteriovenous malformation (disease) | KG + DL |
| 35 | pulmonary arterial hypertension associated with chronic hemolytic anemia | KG + DL |
| 36 | pulmonary arterial hypertension associated with HIV infection | KG + DL |
| 37 | pulmonary arterial hypertension associated with schistosomiasis | KG + DL |
| 38 | pulmonary arterial hypertension associated with connective tissue disease | KG + DL |
| 39 | intermittent vascular claudication | KG + DL |
| 40 | intracranial arteriosclerosis | KG + DL |
| 41 | capillary disease | KG + DL |
| 42 | brachydactyly | KG + DL |
| 43 | nephrogenic syndrome of inappropriate antidiuresis | KG + DL |
| 44 | peripheral arterial disease | KG + DL |
| 45 | hypotrichosis simplex of the scalp | KG + DL |
| 46 | Monckeberg arteriosclerosis | KG + DL |
| 47 | telangiectasia, hereditary hemorrhagic, | KG + DL |
| 48 | congenital hypotrichosis milia | KG + DL |
| 49 | homozygous familial hypercholesterolemia | KG + DL |
| 50 | female breast carcinoma | KG + DL |
(Showing top 50 of 59 predictions)
Disclaimer
These predictions are for research purposes only and do not constitute medical advice. Clinical validation is required before any clinical application.