Zanubrutinib
Basic Information
| Item | Value |
|---|---|
| DrugBank ID | DB15035 |
| Evidence Level | L5 (Computational Prediction) |
| Number of Predicted Indications | 100 |
Predicted Indications (TxGNN)
The following are potential new indications predicted by the TxGNN model. Higher scores indicate higher predicted relevance.
| # | Indication | Source |
|---|---|---|
| 1 | myeloid leukemia | KG + DL |
| 2 | vertebral anomalies and variable endocrine and T-cell dysfunction | KG + DL |
| 3 | ganglioneuroblastoma (disease) | KG + DL |
| 4 | retroperitoneal neoplasm | KG + DL |
| 5 | Ewing sarcoma | KG + DL |
| 6 | neuroblastoma | KG + DL |
| 7 | chronic myelogenous leukemia, BCR-ABL1 positive | KG + DL |
| 8 | blast phase chronic myelogenous leukemia, BCR-ABL1 positive | KG + DL |
| 9 | lymphoma, non-Hodgkin, familial | KG + DL |
| 10 | acute lymphoblastic/lymphocytic leukemia | KG + DL |
| 11 | pregerminal center chronic lymphocytic leukemia/small lymphocytic lymphoma | KG + DL |
| 12 | chronic lymphocytic leukemia/small lymphocytic lymphoma with immunoglobulin heavy chain variable-region gene somatic hypermutation | KG + DL |
| 13 | lymph node cancer | KG + DL |
| 14 | colon adenocarcinoma | KG + DL |
| 15 | plasmacytoma | KG + DL |
| 16 | primary cutaneous T-cell non-Hodgkin lymphoma | KG + DL |
| 17 | primary organ-specific lymphoma | KG + DL |
| 18 | chest wall lymphoma | KG + DL |
| 19 | Hodgkins lymphoma | KG + DL |
| 20 | polyclonal hypergammaglobulinemia | KG + DL |
| 21 | acquired secondary polycythemia | KG + DL |
| 22 | primary cutaneous B-cell lymphoma | KG + DL |
| 23 | polycythemia (disease) | KG + DL |
| 24 | monoclonal paraproteinemia disease | KG + DL |
| 25 | primary cutaneous T-cell lymphoma | KG + DL |
| 26 | Richter syndrome | KG + DL |
| 27 | synovial chondromatosis | KG + DL |
| 28 | orbit sarcoma | KG + DL |
| 29 | congenital secondary polycythemia | KG + DL |
| 30 | liposarcoma | KG + DL |
| 31 | ovarian myxoid liposarcoma | KG + DL |
| 32 | lymphoplasmacytic lymphoma | KG + DL |
| 33 | uterine corpus sarcoma | KG + DL |
| 34 | giant cell tumor of soft tissue | KG + DL |
| 35 | neurolymphomatosis | KG + DL |
| 36 | bone sarcoma | KG + DL |
| 37 | sarcoma, avian | KG + DL |
| 38 | lymphoma | KG + DL |
| 39 | lymphoid neoplasm | KG + DL |
| 40 | metastatic neoplasm | KG + DL |
| 41 | malignant spiradenoma | KG + DL |
| 42 | fibroma of lung | KG + DL |
| 43 | hamartoma of lung | KG + DL |
| 44 | interdigitating dendritic cell sarcoma | KG + DL |
| 45 | pulmonary sulcus neoplasm | KG + DL |
| 46 | lung germ cell tumor | KG + DL |
| 47 | heavy chain disease | KG + DL |
| 48 | subcutaneous panniculitis-like T-cell lymphoma | KG + DL |
| 49 | lung benign neoplasm | KG + DL |
| 50 | marginal zone lymphoma | KG + DL |
(Showing top 50 of 100 predictions)
Disclaimer
These predictions are for research purposes only and do not constitute medical advice. Clinical validation is required before any clinical application.