Inotersen
Basic Information
| Item | Value |
|---|---|
| DrugBank ID | DB14713 |
| Evidence Level | L5 (Computational Prediction) |
| Number of Predicted Indications | 100 |
Predicted Indications (TxGNN)
The following are potential new indications predicted by the TxGNN model. Higher scores indicate higher predicted relevance.
| # | Indication | Source |
|---|---|---|
| 1 | acute intermittent porphyria | KG + DL |
| 2 | appendicitis | KG + DL |
| 3 | IgG4-related pachymeningitis | KG + DL |
| 4 | IgG4-related retroperitoneal fibrosis | KG + DL |
| 5 | non-infectious meningitis | KG + DL |
| 6 | peritonitis | KG + DL |
| 7 | infectious meningitis | KG + DL |
| 8 | IgG4-related mesenteritis | KG + DL |
| 9 | IgG4-related mediastinitis | KG + DL |
| 10 | IgG4-related aortitis | KG + DL |
| 11 | eosinophilic angiocentric fibrosis | KG + DL |
| 12 | chronic meningitis | KG + DL |
| 13 | type I complement component 8 deficiency | KG + DL |
| 14 | rheumatoid arthritis | KG + DL |
| 15 | endocarditis | KG + DL |
| 16 | IgG4-related hepatopathy | KG + DL |
| 17 | porphyria | KG + DL |
| 18 | endocardial fibroelastosis | KG + DL |
| 19 | meningococcal infection | KG + DL |
| 20 | pneumonia | KG + DL |
| 21 | obsolete hyperuricemia (disease) | KG + DL |
| 22 | hereditary persistence of fetal hemoglobin | KG + DL |
| 23 | sclerosing cholangitis | KG + DL |
| 24 | gout | KG + DL |
| 25 | arachnoiditis | KG + DL |
| 26 | meningitis (disease) | KG + DL |
| 27 | colobomatous microphthalmia-rhizomelic dysplasia syndrome | KG + DL |
| 28 | brachydactyly-syndactyly syndrome | KG + DL |
| 29 | type II complement component 8 deficiency | KG + DL |
| 30 | HIV infectious disease | KG + DL |
| 31 | Lesch-Nyhan syndrome | KG + DL |
| 32 | sickle cell anemia | KG + DL |
| 33 | congestive heart failure | KG + DL |
| 34 | scleroderma (disease) | KG + DL |
| 35 | chronic hepatitis B virus infection | KG + DL |
| 36 | bacterial arthritis | KG + DL |
| 37 | hypouricemia, renal | KG + DL |
| 38 | porphyria due to ALA dehydratase deficiency | KG + DL |
| 39 | variegate porphyria | KG + DL |
| 40 | suppurative cholangitis | KG + DL |
| 41 | erythropoietic uroporphyria associated with myeloid malignancy | KG + DL |
| 42 | acute pulmonary heart disease | KG + DL |
| 43 | chronic hepatitis C virus infection | KG + DL |
| 44 | intracranial abscess | KG + DL |
| 45 | female breast carcinoma | KG + DL |
| 46 | neurodevelopmental disorder with ataxic gait, absent speech, and decreased cortical white matter | KG + DL |
| 47 | infectious otitis media | KG + DL |
| 48 | hereditary persistence of fetal hemoglobin-sickle cell disease syndrome | KG + DL |
| 49 | sickle cell-hemoglobin c disease syndrome | KG + DL |
| 50 | sickle cell-hemoglobin d disease syndrome | KG + DL |
(Showing top 50 of 100 predictions)
Disclaimer
These predictions are for research purposes only and do not constitute medical advice. Clinical validation is required before any clinical application.