Lanadelumab
Basic Information
| Item | Value |
|---|---|
| DrugBank ID | DB14597 |
| Evidence Level | L5 (Computational Prediction) |
| Number of Predicted Indications | 100 |
Predicted Indications (TxGNN)
The following are potential new indications predicted by the TxGNN model. Higher scores indicate higher predicted relevance.
| # | Indication | Source |
|---|---|---|
| 1 | C1 inhibitor deficiency | KG + DL |
| 2 | serpinopathy with toxic serpin polymerization | KG + DL |
| 3 | pancreatitis | KG + DL |
| 4 | pseudo-von Willebrand disease | KG + DL |
| 5 | primary release disorder of platelets | KG + DL |
| 6 | immune-mediated necrotizing myopathy | KG + DL |
| 7 | Glanzmann thrombasthenia | KG + DL |
| 8 | antisynthetase syndrome | KG + DL |
| 9 | focal myositis | KG + DL |
| 10 | Scott syndrome | KG + DL |
| 11 | idiopathic eosinophilic myositis | KG + DL |
| 12 | inflammatory myopathy with abundant macrophages | KG + DL |
| 13 | Peyronie disease | KG + DL |
| 14 | alcoholic cardiomyopathy | KG + DL |
| 15 | symptomatic form of hemophilia in female carriers | KG + DL |
| 16 | familial apolipoprotein C-II deficiency | KG + DL |
| 17 | bleeding diathesis due to a collagen receptor defect | KG + DL |
| 18 | hemorrhagic disorder due to a constitutional thrombocytopenia | KG + DL |
| 19 | esophageal varices with bleeding | KG + DL |
| 20 | esophageal varices without bleeding | KG + DL |
| 21 | flood factor deficiency | KG + DL |
| 22 | inherited thrombophilia | KG + DL |
| 23 | thrombotic thrombocytopenic purpura | KG + DL |
| 24 | small bowel Crohn disease | KG + DL |
| 25 | hemophilia | KG + DL |
| 26 | dermatomyositis | KG + DL |
| 27 | varicose disease | KG + DL |
| 28 | acquired coagulation factor deficiency | KG + DL |
| 29 | pernicious anemia | KG + DL |
| 30 | Von Willebrand disease, X-linked form | KG + DL |
| 31 | hereditary thrombocytosis with transverse limb defect | KG + DL |
| 32 | familial thrombomodulin anomalies | KG + DL |
| 33 | hiatus hernia (disease) | KG + DL |
| 34 | gastritis | KG + DL |
| 35 | hyperparathyroidism | KG + DL |
| 36 | lipase deficiency, combined | KG + DL |
| 37 | achlorhydria | KG + DL |
| 38 | hyperphosphatemia (disease) | KG + DL |
| 39 | fetal and neonatal alloimmune thrombocytopenia | KG + DL |
| 40 | myasthenia, limb-girdle, autoimmune | KG + DL |
| 41 | methylcobalamin deficiency type cblG | KG + DL |
| 42 | serpinopathy | KG + DL |
| 43 | venous insufficiency (disease) | KG + DL |
| 44 | pylorospasm | KG + DL |
| 45 | cascade stomach | KG + DL |
| 46 | Dieulafoy lesion | KG + DL |
| 47 | gastric dilatation | KG + DL |
| 48 | cytosolic phospholipase-A2 alpha deficiency associated bleeding disorder | KG + DL |
| 49 | myasthenia gravis with thymus hyperplasia | KG + DL |
| 50 | Camurati-Engelmann disease | KG + DL |
(Showing top 50 of 100 predictions)
Disclaimer
These predictions are for research purposes only and do not constitute medical advice. Clinical validation is required before any clinical application.