Emicizumab
Basic Information
| Item | Value |
|---|---|
| DrugBank ID | DB13923 |
| Evidence Level | L5 (Computational Prediction) |
| Number of Predicted Indications | 54 |
Predicted Indications (TxGNN)
The following are potential new indications predicted by the TxGNN model. Higher scores indicate higher predicted relevance.
| # | Indication | Source |
|---|---|---|
| 1 | pseudo-von Willebrand disease | KG + DL |
| 2 | primary release disorder of platelets | KG + DL |
| 3 | Glanzmann thrombasthenia | KG + DL |
| 4 | Scott syndrome | KG + DL |
| 5 | acquired coagulation factor deficiency | KG + DL |
| 6 | bleeding diathesis due to a collagen receptor defect | KG + DL |
| 7 | hemorrhagic disorder due to a constitutional thrombocytopenia | KG + DL |
| 8 | thrombotic thrombocytopenic purpura | KG + DL |
| 9 | fetal and neonatal alloimmune thrombocytopenia | KG + DL |
| 10 | flood factor deficiency | KG + DL |
| 11 | hereditary thrombocytosis with transverse limb defect | KG + DL |
| 12 | familial thrombomodulin anomalies | KG + DL |
| 13 | inherited thrombophilia | KG + DL |
| 14 | platelet-type bleeding disorder | KG + DL |
| 15 | hemophilia A with vascular abnormality | KG + DL |
| 16 | methylcobalamin deficiency type cblG | KG + DL |
| 17 | Ehlers-Danlos syndrome, fibronectinemic type | KG + DL |
| 18 | factor XI deficiency | KG + DL |
| 19 | hemorrhagic disorder due to a platelet anomaly | KG + DL |
| 20 | C1 inhibitor deficiency | KG + DL |
| 21 | thrombocytopenic purpura | KG + DL |
| 22 | serpinopathy with toxic serpin polymerization | KG + DL |
| 23 | congenital factor V deficiency | KG + DL |
| 24 | factor XIII, A subunit, deficiency | KG + DL |
| 25 | congenital factor XIII deficiency | KG + DL |
| 26 | prothrombin deficiency | KG + DL |
| 27 | Tatsumi factor deficiency | KG + DL |
| 28 | multiple sclerosis-ichthyosis-factor VIII deficiency syndrome | KG + DL |
| 29 | inherited prekallikrein deficiency | KG + DL |
| 30 | acquired hemophilia | KG + DL |
| 31 | congenital factor XI deficiency | KG + DL |
| 32 | hereditary angioedema with C1Inh deficiency | KG + DL |
| 33 | hemorrhagic disorder due to a coagulation factors defect | KG + DL |
| 34 | congenital plasminogen activator inhibitor type 1 deficiency | KG + DL |
| 35 | esophageal varices without bleeding | KG + DL |
| 36 | esophageal varices with bleeding | KG + DL |
| 37 | familial apolipoprotein C-II deficiency | KG + DL |
| 38 | immune-mediated necrotizing myopathy | KG + DL |
| 39 | antisynthetase syndrome | KG + DL |
| 40 | focal myositis | KG + DL |
| 41 | factor X deficiency | KG + DL |
| 42 | varicose disease | KG + DL |
| 43 | von Willebrand disease (hereditary or acquired) | KG + DL |
| 44 | inflammatory myopathy with abundant macrophages | KG + DL |
| 45 | idiopathic eosinophilic myositis | KG + DL |
| 46 | coagulation protein disease | KG + DL |
| 47 | hemorrhagic disease of newborn | KG + DL |
| 48 | factor XIII deficiency | KG + DL |
| 49 | Ledderhose disease | KG + DL |
| 50 | infantile digital fibromatosis | KG + DL |
(Showing top 50 of 54 predictions)
Disclaimer
These predictions are for research purposes only and do not constitute medical advice. Clinical validation is required before any clinical application.