Lusutrombopag
Basic Information
| Item | Value |
|---|---|
| DrugBank ID | DB13125 |
| Evidence Level | L5 (Computational Prediction) |
| Number of Predicted Indications | 79 |
Predicted Indications (TxGNN)
The following are potential new indications predicted by the TxGNN model. Higher scores indicate higher predicted relevance.
| # | Indication | Source |
|---|---|---|
| 1 | hereditary thrombocytopenia with normal platelets | KG + DL |
| 2 | marcothrombocytopenia with mitral valve insufficiency | KG + DL |
| 3 | transient neonatal thrombocytopenia | KG + DL |
| 4 | dense granule disease | KG + DL |
| 5 | platelet storage pool deficiency | KG + DL |
| 6 | amyotrophic lateral sclerosis | KG + DL |
| 7 | lower motor neuron syndrome with late-adult onset | KG + DL |
| 8 | amyotrophic lateral sclerosis, susceptibility to | KG + DL |
| 9 | bilateral parasagittal parieto-occipital polymicrogyria | KG + DL |
| 10 | axial spondylometaphyseal dysplasia | KG + DL |
| 11 | amyotrohpic lateral sclerosis type 22 | KG + DL |
| 12 | Mills syndrome | KG + DL |
| 13 | monomelic amyotrophy | KG + DL |
| 14 | trichomegaly-retina pigmentary degeneration-dwarfism syndrome | KG + DL |
| 15 | autosomal dominant mitochondrial myopathy with exercise intolerance | KG + DL |
| 16 | lethal arthrogryposis-anterior horn cell disease syndrome | KG + DL |
| 17 | kidney pelvis sarcomatoid transitional cell carcinoma | KG + DL |
| 18 | neuronopathy, distal hereditary motor | KG + DL |
| 19 | prostatic urethra urothelial carcinoma | KG + DL |
| 20 | infiltrating bladder urothelial carcinoma sarcomatoid variant | KG + DL |
| 21 | renal pelvis papillary urothelial carcinoma | KG + DL |
| 22 | progeria-short stature-pigmented nevi syndrome | KG + DL |
| 23 | X-linked lymphoproliferative disease due to SH2D1A deficiency | KG + DL |
| 24 | progeroid syndrome, Petty type | KG + DL |
| 25 | A20 haploinsufficiency | KG + DL |
| 26 | immune dysregulation with inflammatory bowel disease | KG + DL |
| 27 | hemophagocytic syndrome associated with an infection | KG + DL |
| 28 | acquired hemophagocytic lymphohistiocytosis associated with malignant disease | KG + DL |
| 29 | glaucoma | KG + DL |
| 30 | proteinuria | KG + DL |
| 31 | CMM7 | KG + DL |
| 32 | pediatric leptomeningeal melanoma | KG + DL |
| 33 | melanoma | KG + DL |
| 34 | epithelioid cell uveal melanoma | KG + DL |
| 35 | vulvar melanoma (disease) | KG + DL |
| 36 | rhabdoid tumor | KG + DL |
| 37 | primary CD59 deficiency | KG + DL |
| 38 | neonatal autoimmune hemolytic anemia | KG + DL |
| 39 | leukonychia totalis-acanthosis-nigricans-like lesions-abnormal hair syndrome | KG + DL |
| 40 | mixed-type autoimmune hemolytic anemia | KG + DL |
| 41 | familial generalized lentiginosis | KG + DL |
| 42 | acromelanosis | KG + DL |
| 43 | congenital multiple café-au-lait macules-increased sister chromatid exchange syndrome | KG + DL |
| 44 | cold agglutinin disease | KG + DL |
| 45 | drug-induced autoimmune hemolytic anemia | KG + DL |
| 46 | human herpesvirus 8-related tumor | KG + DL |
| 47 | hemophagocytic lymphohistiocytosis | KG + DL |
| 48 | bartholin gland carcinoma | KG + DL |
| 49 | severe combined immunodeficiency due to LAT deficiency | KG + DL |
| 50 | intellectual disability, autosomal dominant 55, with seizures | KG + DL |
(Showing top 50 of 79 predictions)
Disclaimer
These predictions are for research purposes only and do not constitute medical advice. Clinical validation is required before any clinical application.