Conestat Alfa
Basic Information
| Item | Value |
|---|---|
| DrugBank ID | DB09228 |
| Evidence Level | L5 (Computational Prediction) |
| Number of Predicted Indications | 69 |
Predicted Indications (TxGNN)
The following are potential new indications predicted by the TxGNN model. Higher scores indicate higher predicted relevance.
| # | Indication | Source |
|---|---|---|
| 1 | C1 inhibitor deficiency | KG + DL |
| 2 | serpinopathy with toxic serpin polymerization | KG + DL |
| 3 | hereditary angioedema with C1Inh deficiency | KG + DL |
| 4 | primary release disorder of platelets | KG + DL |
| 5 | pseudo-von Willebrand disease | KG + DL |
| 6 | Glanzmann thrombasthenia | KG + DL |
| 7 | Scott syndrome | KG + DL |
| 8 | hemorrhagic disorder due to a constitutional thrombocytopenia | KG + DL |
| 9 | bleeding diathesis due to a collagen receptor defect | KG + DL |
| 10 | fetal and neonatal alloimmune thrombocytopenia | KG + DL |
| 11 | autoimmune thrombocytopenic | KG + DL |
| 12 | pancreatitis | KG + DL |
| 13 | thrombotic thrombocytopenic purpura | KG + DL |
| 14 | platelet-type bleeding disorder | KG + DL |
| 15 | immune-mediated necrotizing myopathy | KG + DL |
| 16 | antisynthetase syndrome | KG + DL |
| 17 | focal myositis | KG + DL |
| 18 | Evans syndrome | KG + DL |
| 19 | thrombocytopenia due to immune destruction | KG + DL |
| 20 | flood factor deficiency | KG + DL |
| 21 | inflammatory myopathy with abundant macrophages | KG + DL |
| 22 | idiopathic eosinophilic myositis | KG + DL |
| 23 | Ehlers-Danlos syndrome, fibronectinemic type | KG + DL |
| 24 | inherited thrombophilia | KG + DL |
| 25 | hereditary thrombocytosis with transverse limb defect | KG + DL |
| 26 | familial thrombomodulin anomalies | KG + DL |
| 27 | venous insufficiency (disease) | KG + DL |
| 28 | Peyronie disease | KG + DL |
| 29 | neonatal thrombocytopenia | KG + DL |
| 30 | cytosolic phospholipase-A2 alpha deficiency associated bleeding disorder | KG + DL |
| 31 | methylcobalamin deficiency type cblG | KG + DL |
| 32 | congenital factor V deficiency | KG + DL |
| 33 | dermatomyositis | KG + DL |
| 34 | alcoholic cardiomyopathy | KG + DL |
| 35 | infantile digital fibromatosis | KG + DL |
| 36 | Ledderhose disease | KG + DL |
| 37 | palmar fibromatosis | KG + DL |
| 38 | penile fibromatosis | KG + DL |
| 39 | esophageal varices with bleeding | KG + DL |
| 40 | esophageal varices without bleeding | KG + DL |
| 41 | Camurati-Engelmann disease | KG + DL |
| 42 | autosomal dominant macrothrombocytopenia | KG + DL |
| 43 | posterior leukoencephalopathy syndrome | KG + DL |
| 44 | blood platelet disease | KG + DL |
| 45 | small bowel Crohn disease | KG + DL |
| 46 | serpinopathy | KG + DL |
| 47 | acquired coagulation factor deficiency | KG + DL |
| 48 | varicose disease | KG + DL |
| 49 | hemophilia | KG + DL |
| 50 | primary hyperoxaluria | KG + DL |
(Showing top 50 of 69 predictions)
Disclaimer
These predictions are for research purposes only and do not constitute medical advice. Clinical validation is required before any clinical application.