Alglucosidase Alfa
Basic Information
| Item | Value |
|---|---|
| DrugBank ID | DB01272 |
| Evidence Level | L5 (Computational Prediction) |
| Number of Predicted Indications | 48 |
Predicted Indications (TxGNN)
The following are potential new indications predicted by the TxGNN model. Higher scores indicate higher predicted relevance.
| # | Indication | Source |
|---|---|---|
| 1 | adult polyglucosan body disease | KG + DL |
| 2 | glycogen storage disease due to glycogen branching enzyme deficiency, congenital neuromuscular form | KG + DL |
| 3 | glycogen storage disease due to glycogen branching enzyme deficiency, fatal perinatal neuromuscular form | KG + DL |
| 4 | congenital entropion | KG + DL |
| 5 | congenital ectropion | KG + DL |
| 6 | congenital Horner syndrome (disease) | KG + DL |
| 7 | ptosis-vocal cord paralysis syndrome | KG + DL |
| 8 | camptodactyly, myopia, and fibrosis of the medial rectus muscle of eye | KG + DL |
| 9 | epiblepharon | KG + DL |
| 10 | ptosis-strabismus-ectopic pupils syndrome | KG + DL |
| 11 | tricarboxylic acid cycle disorder | KG + DL |
| 12 | ptosis-upper ocular movement limitation-absence of lacrimal punctum syndrome | KG + DL |
| 13 | mucopolysaccharidosis | KG + DL |
| 14 | jaw-winking syndrome | KG + DL |
| 15 | disease of transporter activity | KG + DL |
| 16 | glycogen storage disease due to glycogen branching enzyme deficiency, childhood combined hepatic and myopathic form | KG + DL |
| 17 | glycogen storage disease due to glycogen branching enzyme deficiency, progressive hepatic form | KG + DL |
| 18 | glycogen storage disease due to glycogen branching enzyme deficiency, adult neuromuscular form | KG + DL |
| 19 | glycogen storage disease due to glycogen branching enzyme deficiency, childhood neuromuscular form | KG + DL |
| 20 | glycogen storage disease due to glycogen branching enzyme deficiency, non progressive hepatic form | KG + DL |
| 21 | renal tubular acidosis | KG + DL |
| 22 | pyruvate metabolism disorder | KG + DL |
| 23 | inborn disorder of fatty acid oxidation and ketone body metabolism | KG + DL |
| 24 | Scheie syndrome | KG + DL |
| 25 | Sanfilippo syndrome | KG + DL |
| 26 | inborn disorder of lysosomal amino acid transport | KG + DL |
| 27 | Charcot-Marie-Tooth disease | KG + DL |
| 28 | hemolytic anemia due to diphosphoglycerate mutase deficiency | KG + DL |
| 29 | glycogen storage disease due to glucose-6-phosphatase deficiency | KG + DL |
| 30 | mitochondrial oxidative phosphorylation disorder due to nuclear DNA anomalies | KG + DL |
| 31 | lysosomal storage disease with skeletal involvement | KG + DL |
| 32 | ocular cystinosis | KG + DL |
| 33 | primary immunodeficiency syndrome due to p14 deficiency | KG + DL |
| 34 | Steel syndrome | KG + DL |
| 35 | Pendred syndrome | KG + DL |
| 36 | neutropenia-monocytopenia-deafness syndrome | KG + DL |
| 37 | monosomy X | KG + DL |
| 38 | metaphyseal dysplasia without hypotrichosis | KG + DL |
| 39 | growth hormone insensitivity syndrome with immune dysregulation 2, autosomal dominant | KG + DL |
| 40 | galactosemia | KG + DL |
| 41 | Barth syndrome | KG + DL |
| 42 | hypophosphatasia | KG + DL |
| 43 | autosomal recessive nonsyndromic deafness | KG + DL |
| 44 | Wolfram syndrome | KG + DL |
| 45 | osteopetrosis | KG + DL |
| 46 | phosphoribosylpyrophosphate synthetase superactivity | KG + DL |
| 47 | leukocyte adhesion deficiency | KG + DL |
| 48 | deafness dystonia syndrome | KG + DL |
Disclaimer
These predictions are for research purposes only and do not constitute medical advice. Clinical validation is required before any clinical application.