Vigabatrin
Basic Information
| Item | Value |
|---|---|
| DrugBank ID | DB01080 |
| Evidence Level | L5 (Computational Prediction) |
| Number of Predicted Indications | 43 |
Predicted Indications (TxGNN)
The following are potential new indications predicted by the TxGNN model. Higher scores indicate higher predicted relevance.
| # | Indication | Source |
|---|---|---|
| 1 | intellectual disability, X-linked, with or without seizures, arx-related | KG + DL |
| 2 | episodic kinesigenic dyskinesia | KG + DL |
| 3 | 1q44 microdeletion syndrome | KG + DL |
| 4 | PURA-related severe neonatal hypotonia-seizures-encephalopathy syndrome due to a point mutation | KG + DL |
| 5 | DK1-CDG | KG + DL |
| 6 | microtriplication 11q24.1 | KG + DL |
| 7 | CCDC115-CDG | KG + DL |
| 8 | neonatal period electroclinical syndrome | KG + DL |
| 9 | genetic lethal multiple congenital anomalies/dysmorphic syndrome | KG + DL |
| 10 | COG2-CDG | KG + DL |
| 11 | colobomatous microphthalmia - obesity - hypogenitalism - intellectual disability syndrome | KG + DL |
| 12 | X-linked dominant intellectual disability-epilepsy syndrome | KG + DL |
| 13 | male hypergonadotropic hypogonadism-intellectual disability-skeletal anomalies syndrome | KG + DL |
| 14 | Jawad syndrome | KG + DL |
| 15 | muscular hypertrophy-hepatomegaly-polyhydramnios syndrome | KG + DL |
| 16 | infancy electroclinical syndrome | KG + DL |
| 17 | neonatal epileptic encephalopathy | KG + DL |
| 18 | craniofaciofrontodigital syndrome | KG + DL |
| 19 | blepharophimosis - intellectual disability syndrome, MKB type | KG + DL |
| 20 | pancreatic agenesis-holoprosencephaly syndrome | KG + DL |
| 21 | ALG12-CDG | KG + DL |
| 22 | microcephaly-intellectual disability-phalangeal and neurological anomalies syndrome | KG + DL |
| 23 | defect in V-ATPase | KG + DL |
| 24 | myoclonic epilepsy, Hartung type | KG + DL |
| 25 | Crane-Heise syndrome | KG + DL |
| 26 | faciocardiorenal syndrome | KG + DL |
| 27 | X-linked intellectual disability-global development delay-facial dysmorphism-sacral caudal remnant syndrome | KG + DL |
| 28 | XYLT1-CDG | KG + DL |
| 29 | arachnodactyly-abnormal ossification-intellectual disability syndrome | KG + DL |
| 30 | telecanthus-hypertelorism-strabismus-pes cavus syndrome | KG + DL |
| 31 | malignant migrating partial seizures of infancy | KG + DL |
| 32 | macrocephaly-short stature-paraplegia syndrome | KG + DL |
| 33 | microcephaly-short stature-intellectual disability-facial dysmorphism syndrome | KG + DL |
| 34 | trigeminal nerve neoplasm | KG + DL |
| 35 | pseudoachondroplasia | KG + DL |
| 36 | epilepsy of infancy with migrating focal seizures | KG + DL |
| 37 | myoclonic encephalopathy in non-progressive disorder | KG + DL |
| 38 | self-limited familial and non-familial neonatal/infantile seizures | KG + DL |
| 39 | adolescent/adult onset autosomal dominant epilepsy with auditory features | KG + DL |
| 40 | restless legs syndrome | KG + DL |
| 41 | osteoarthritis | KG + DL |
| 42 | myoclonic-atonic epilepsy | KG + DL |
| 43 | guanidinoacetate methyltransferase deficiency | KG + DL |
Disclaimer
These predictions are for research purposes only and do not constitute medical advice. Clinical validation is required before any clinical application.