Treprostinil
Basic Information
| Item | Value |
|---|---|
| DrugBank ID | DB00374 |
| Evidence Level | L5 (Computational Prediction) |
| Number of Predicted Indications | 33 |
Predicted Indications (TxGNN)
The following are potential new indications predicted by the TxGNN model. Higher scores indicate higher predicted relevance.
| # | Indication | Source |
|---|---|---|
| 1 | pulmonary arteriovenous malformation (disease) | KG + DL |
| 2 | pulmonary arterial hypertension associated with congenital heart disease | KG + DL |
| 3 | pulmonary arterial hypertension associated with connective tissue disease | KG + DL |
| 4 | pulmonary arterial hypertension associated with chronic hemolytic anemia | KG + DL |
| 5 | pulmonary arterial hypertension associated with HIV infection | KG + DL |
| 6 | pulmonary arterial hypertension associated with schistosomiasis | KG + DL |
| 7 | hypotrichosis simplex of the scalp | KG + DL |
| 8 | congenital hypotrichosis milia | KG + DL |
| 9 | malformation syndrome with odontal and/or periodontal component | KG + DL |
| 10 | Ambras type hypertrichosis universalis congenita | KG + DL |
| 11 | diffuse alopecia areata | KG + DL |
| 12 | hypertrichosis (disease) | KG + DL |
| 13 | syndrome with a Dandy-Walker malformation as major feature | KG + DL |
| 14 | isolated genetic hair shaft abnormality | KG + DL |
| 15 | alopecia | KG + DL |
| 16 | pulmonary hypertension, primary, autosomal recessive | KG + DL |
| 17 | obsolete patella aplasia, coxa vara, and tarsal synostosis | KG + DL |
| 18 | telangiectasia, hereditary hemorrhagic, | KG + DL |
| 19 | familial clubfoot due to 17q23.1q23.2 microduplication | KG + DL |
| 20 | chromosome 17q23.1-q23.2 deletion syndrome | KG + DL |
| 21 | coxopodopatellar syndrome | KG + DL |
| 22 | pulmonary hypertension, primary | KG + DL |
| 23 | idiopathic pulmonary arterial hypertension | KG + DL |
| 24 | idiopathic and/or familial pulmonary arterial hypertension | KG + DL |
| 25 | heritable pulmonary arterial hypertension | KG + DL |
| 26 | juvenile polyposis syndrome | KG + DL |
| 27 | persistent fetal circulation syndrome | KG + DL |
| 28 | genetic alopecia | KG + DL |
| 29 | pulmonary hypertension | KG + DL |
| 30 | gastrointestinal hamartoma | KG + DL |
| 31 | acute myeloid leukemia with abnormal bone marrow eosinophils inv(16)(p13q22) or t(16;16)(p13;q22) | KG + DL |
| 32 | kyphoscoliotic heart disease | KG + DL |
| 33 | brachydactyly | KG + DL |
Disclaimer
These predictions are for research purposes only and do not constitute medical advice. Clinical validation is required before any clinical application.