Becaplermin
Basic Information
| Item | Value |
|---|---|
| DrugBank ID | DB00102 |
| Evidence Level | L5 (Computational Prediction) |
| Number of Predicted Indications | 100 |
Predicted Indications (TxGNN)
The following are potential new indications predicted by the TxGNN model. Higher scores indicate higher predicted relevance.
| # | Indication | Source |
|---|---|---|
| 1 | amenorrhea (disease) | KG + DL |
| 2 | erectile dysfunction (disease) | KG + DL |
| 3 | HER2 positive breast carcinoma | KG + DL |
| 4 | progesterone-receptor negative breast cancer | KG + DL |
| 5 | pulmonary hypertension | KG + DL |
| 6 | normal breast-like subtype of breast carcinoma | KG + DL |
| 7 | progesterone-receptor positive breast cancer | KG + DL |
| 8 | breast tumor luminal A or B | KG + DL |
| 9 | hypogonadotropic hypogonadism with or without anosmia | KG + DL |
| 10 | Leydig cell hypoplasia due to LH resistance | KG + DL |
| 11 | 46,XY disorder of sex development due to impaired androgen production | KG + DL |
| 12 | cytomegalovirus infection | KG + DL |
| 13 | adrenal gland hyperfunction | KG + DL |
| 14 | infectious bovine rhinotracheitis | KG + DL |
| 15 | malignant catarrh | KG + DL |
| 16 | kyphoscoliotic heart disease | KG + DL |
| 17 | migraine disorder | KG + DL |
| 18 | multiple endocrine neoplasia | KG + DL |
| 19 | coxopodopatellar syndrome | KG + DL |
| 20 | familial clubfoot due to 17q23.1q23.2 microduplication | KG + DL |
| 21 | chromosome 17q23.1-q23.2 deletion syndrome | KG + DL |
| 22 | idiopathic pulmonary arterial hypertension | KG + DL |
| 23 | pulmonary hypertension, primary, autosomal recessive | KG + DL |
| 24 | obsolete patella aplasia, coxa vara, and tarsal synostosis | KG + DL |
| 25 | elephantiasis | KG + DL |
| 26 | migraine with brainstem aura | KG + DL |
| 27 | double outlet right ventricle with subaortic or doubly committed ventricular septal defect with pulmonary stenosis | KG + DL |
| 28 | transitional cell carcinoma | KG + DL |
| 29 | pulmonary arterial hypertension | KG + DL |
| 30 | gastrointestinal hamartoma | KG + DL |
| 31 | prostatic urethra urothelial carcinoma | KG + DL |
| 32 | pulmonary hypertension, primary | KG + DL |
| 33 | acrofacial dysostosis, Palagonia type | KG + DL |
| 34 | Treacher-Collins syndrome 1 | KG + DL |
| 35 | kidney pelvis sarcomatoid transitional cell carcinoma | KG + DL |
| 36 | Ewing sarcoma | KG + DL |
| 37 | double outlet right ventricle with atrioventricular septal defect, pulmonary stenosis, heterotaxy | KG + DL |
| 38 | infiltrating bladder urothelial carcinoma sarcomatoid variant | KG + DL |
| 39 | Nager acrofacial dysostosis | KG + DL |
| 40 | renal pelvis papillary urothelial carcinoma | KG + DL |
| 41 | tubular variant testicular seminoma | KG + DL |
| 42 | primary cutaneous T-cell lymphoma | KG + DL |
| 43 | esotropia | KG + DL |
| 44 | acrofacial dysostosis | KG + DL |
| 45 | persistent fetal circulation syndrome | KG + DL |
| 46 | spermatocytic seminoma | KG + DL |
| 47 | angioma serpiginosum | KG + DL |
| 48 | idiopathic and/or familial pulmonary arterial hypertension | KG + DL |
| 49 | Raynaud disease | KG + DL |
| 50 | isolated growth hormone deficiency | KG + DL |
(Showing top 50 of 100 predictions)
Disclaimer
These predictions are for research purposes only and do not constitute medical advice. Clinical validation is required before any clinical application.