Dornase Alfa
Basic Information
| Item | Value |
|---|---|
| DrugBank ID | DB00003 |
| Evidence Level | L5 (Computational Prediction) |
| Number of Predicted Indications | 100 |
Predicted Indications (TxGNN)
The following are potential new indications predicted by the TxGNN model. Higher scores indicate higher predicted relevance.
| # | Indication | Source |
|---|---|---|
| 1 | oculotrichodysplasia | KG + DL |
| 2 | blood group, lewis system | KG + DL |
| 3 | immune dysregulation-inflammatory bowel disease-arthritis-recurrent infections-lymphopenia syndrome | KG + DL |
| 4 | spastic ataxia-dysarthria due to glutaminase deficiency | KG + DL |
| 5 | idiopathic gastroparesis | KG + DL |
| 6 | primary biliary cholangitis/primary sclerosing cholangitis and autoimmune hepatitis overlap syndrome | KG + DL |
| 7 | methotrexate toxicity | KG + DL |
| 8 | primary desmosis coli | KG + DL |
| 9 | serine biosynthesis pathway deficiency, infantile/juvenile form | KG + DL |
| 10 | isolated mesenteric vein thrombosis | KG + DL |
| 11 | PUM1-associated developmental disability-ataxia-seizure syndrome | KG + DL |
| 12 | GRIN2B-related developmental delay, intellectual disability and autism spectrum disorder | KG + DL |
| 13 | PHIP-related behavioral problems-intellectual disability-obesity-dysmorphic features syndrome | KG + DL |
| 14 | Mills syndrome | KG + DL |
| 15 | punctate acrokeratoderma freckle-like pigmentation | KG + DL |
| 16 | congestive splenomegaly | KG + DL |
| 17 | cauda equina cancer | KG + DL |
| 18 | autosomal dominant oculocutaneous albinism | KG + DL |
| 19 | malignant peritoneal germ cell tumor | KG + DL |
| 20 | toxic amblyopia | KG + DL |
| 21 | Far-East scarlet-like fever | KG + DL |
| 22 | ergotism | KG + DL |
| 23 | Sammartino-Decreccio syndrome | KG + DL |
| 24 | Samson-Viljoen syndrome | KG + DL |
| 25 | Sandhaus-Ben-Ami syndrome | KG + DL |
| 26 | prostatic malacoplakia associated with prostatic abscess | KG + DL |
| 27 | macrocephaly, intellectual disability, short stature, spastic paraplegia and cns malformations | KG + DL |
| 28 | Say-Carpenter syndrome | KG + DL |
| 29 | Schwartz-Cohen-addad-Lambert syndrome | KG + DL |
| 30 | Schrander-stumpel-Theunissen-Hulsmans syndrome | KG + DL |
| 31 | Vagneur-Triolle-Ripert syndrome | KG + DL |
| 32 | Sackey-Sakati-Aur syndrome | KG + DL |
| 33 | Slti-Salem syndrome | KG + DL |
| 34 | rheumatic disease of mitral valve | KG + DL |
| 35 | pseudoachondroplastic dysplasia 2 | KG + DL |
| 36 | Weil’s disease | KG + DL |
| 37 | Zazam Sheriff Phillips syndrome | KG + DL |
| 38 | neuroaxonal dystrophy renal tubular acidosis | KG + DL |
| 39 | coronal synostosis, syndactyly and jejunal atresia | KG + DL |
| 40 | thickened earlobes with conductive deafness from incus-stapes abnormalities | KG + DL |
| 41 | ichthyosis, follicular | KG + DL |
| 42 | Hordnes Engebretsen Knudtson syndrome | KG + DL |
| 43 | hypothyroidism due to iodide transport defect | KG + DL |
| 44 | jones hersh yusk syndrome | KG + DL |
| 45 | Landy-Donnai syndrome | KG + DL |
| 46 | male pseudohermaphroditism due to defective lh molecule | KG + DL |
| 47 | mcpherson robertson cammarano syndrome | KG + DL |
| 48 | merlob grunebaum reisner syndrome | KG + DL |
| 49 | microcephaly micropenis convulsions | KG + DL |
| 50 | isolated microcephaly | KG + DL |
(Showing top 50 of 100 predictions)
Disclaimer
These predictions are for research purposes only and do not constitute medical advice. Clinical validation is required before any clinical application.